March 6: Aspirin.Molecule of Aspirin

Aspirin appeared and used fro treatment of headache alone or in combination with paracetamol and caffeine long time back .It was very much an effective remedy.But is notorious to cause stomach problem in form of gastritis, ulcers and bleeding.Then it was not used for many years till its beneficial effect in myocardial ischaemia and infarction was rediscovered.In low doses, as low as 75 mgs per day is prescribed to myocardial infarction patients to keep their blood more fluid i.e. to prevent thrombosis.It is also prescribed in combination with other thrombolytic agents.The advantage it has is low cost and easy availability. It is said that if heart attack is suspected and nothing is found a tablet of aspirin will prevent much damage to heart muscle.The potential side effect ,gastrointestinal bleeding can be prevented by other anti-ulcerogenic drugs. 
Researchers also say that aspirin helps in early diagnosis of colon cancer.The hall mark of colon cancer is painless  bleeding per anus besides other symptoms.the bleeding tendency is probably facilitated by aspirin.
It is still the drug of choice for a very important disease called Rheumatic arthritis having much dreaded sequelae  of rheumatic heart disease.
So in right doses and judicious combination it is a panacea for health.

myocardial infarction - Myokardinfarkt - scheme1) Blocked Coronary Artery,2)Ischaemic heart muscle.

Pain in acute myocardial infarction (front)Distribution Of Pain Of Heart Attack.
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  1. #1 by Chloe Anderson on May 20, 2010 - 3:38 am

    my uncle got stomach ulcers because he took a lot of Aspirin to take care of his high blood pressure.’~’

    • #2 by Dr.Prahallad on May 20, 2010 - 1:31 pm

      Excess is always bad. But, ulcers may not cause death as such, unless there is a fatal bleeding episode. Ulcers can be treated. Perhaps, death might have been due to some complication of high blood pressure. We are sorry for that.

  2. #3 by Physlenny on June 8, 2010 - 9:31 am

    Great article . Will definitely copy it to my website.

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