New Test Predicting Breast Cancer Relapse

A five-gene signature related to tumour infiltrating immune cells can accurately predict relapse-free survival in breast cancer.

Amplify’d from medicalxpress.com

New biomarker that predicts breast cancer relapse found

Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new biomarker related to the body’s immune system that can predict a breast cancer patients’ risk of cancer recurrence. This breakthrough may lead to new genetic testing that further personalizes breast cancer care.

The study, published in the journal Breast Cancer Research and Treatment, is the first to use tumor infiltrating immune cells located at the site of the tumor to predict cancer recurrence. Using tissue samples from breast cancer patients, researchers found that a specific, five-gene signature related to tumor infiltrating immune cells can accurately predict relapse-free survival. Currently, there are two main tests used to predict the risk of relapse in breast cancer patients, the Oncotype DX panel and the MammaPrint panel. Both of these tests focus on genes that are mainly expressed by tumor cells.

Read more at medicalxpress.com

 

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