Detecting Abnormal Cells by Light

Detecting abnormal cells by light; invented by Duke Researchers.

Amplify’d from

A flashlight that detects cancer

The way we diagnose cancer nowadays is usually pretty invasive.

It usually starts with biopsies, which remove tissue samples that can be sent out to a lab and checked for abnormalities.

Instead, it’s like a thin wand (often flexible) with a light on the end, similar to an endoscope, which can snake into a person’s organs, such as into their gastrointestinal tract to see the stomach.

The cancer-spotting version can emit short bursts of light that will show the inside of a cell, exposing whether the nuclei look precancerous, meaning whether they look deformed or are larger than the nuclei of healthy cells.

And it does all this without removing or dyeing any tissue.

So far, the Duke researchers have tested their invention in the esophagus and colon (from a small sample size, it has 85% accuracy).

This approach could be the future of diagnosing [precancerous cells] of the colon. The old-fashioned techniques we use haven’t changed in years. This could be a real game-changer in how we detect, characterize and even treat pre-cancerous or cancerous lesions. For some gastrointestinal biopsies, the procedure itself has inherent risks such as bleeding or perforation, so a non-invasive technique could greatly improve a patient’s quality of life.




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